Research Article

Report on the incidence of hereditary disorders (BLAD, DUMPS) in the Polish population of Holstein-Friesian cattle

Marta Gozdek 1, Magdalena Kolenda 2, Dariusz Kamola 1,3, Beata Sitkowska 2 

1Polish Federation of Cattle Breeders and Dairy Farmers in Warsaw

2Department of Biotechnology and Animal Genetics, Faculty of Animal Breeding and Biology, UTP University of Science and Technology

3Division of Dietetics, Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences (SGGW)

Abstract. BLAD (bovine leukocyte adhesion deficiency) and DUMPS (deficiency of uridine monophosphate synthase) are hereditary lethal autosomal recessive disorders that may affect Holstein cattle. The aim of the present study was to evaluate the frequency of BLAD and DUMPS genotypes in the Polish population of dairy cows. In the study 5 732 Polish Holstein-Friesian females were genetically tested for BLAD and DUMPS. Results of the present study indicate that the Polish population of dairy cattle is free from DUMPS as there were not carriers nor sick animals. For BLAD the study confirmed the present of carriers in the population to be at a low value (0.21%). Both BLAD and DUMPS may strongly affect the profitability of a dairy farm, therefore, in order to avoid the economic losses caused by the presence of these genetic disorders in the herd it is important to screen the population and detect carriers as soon as possible.

Keywords: BLAD, DUMPS, cattle, gene frequency, microarrays

 

This Article
Article in Press

Received: 15 Jul 2020

Accepted: 9 Sep 2020

Published online: 15 Sep 2020

Accesses: 22

How to cite

Gozdek, M., Kolenda, M., Kamola, D., Sitkowska, B., (2020). Report on the incidence of hereditary disorders (BLAD, DUMPS) in the Polish population of Holstein-Friesian cattle. Acta Sci. Pol. Zootechnica, 19(3), in press.