Review Article

Development and validation the efficacy of Bacillus-based fermented products as an antibiotics alternative in domestic animals

Yeong-Hsiang Cheng 1, Yi-Bing Horng1, Wei-Jung Chen 1, Kuo-Feng Hua 1, Andrzej Dybus 2, Felix Shih-Hsiang Hsiao 3, Yu-Hsiang Yu 1 

1National Ilan University, Department of Biotechnology and Animal Science, Taiwan

2Department of Genetics, West Pomeranian University of Technology, Szczecin, Poland

3Tunghai University, Department of Animal Science and Biotechnology, Taiwan

Abstract. Intestinal microflora plays a critical role in the process of nutrient digestion and immunomodulation. Normal gut microbiota is responsible for resistance to colonization by exogenous pathogenic microorganisms. Pathogen invasion alters the intestinal microbiota composition and causes intestinal disorder in domestic animals. Moreover, stress, infection, or dysbiosis during the feeding period also results in an imbalanced gut microbiota, which also leads to postweaning diarrhea of piglets and necrotic enteritis of chickens. It has been demonstrated that B. licheniformis and B. subtilis has antimicrobial activity against pathogens through the production of antibacterial cyclic lipopeptide surfactin. Therefore, in the present review a series research works on the Bacillus based-fermented products efficacy and validation by alleviating the diarrhea incidence, enteritis, coccidiosis, modified gut microbiota, and decrease postpartum dysgalactia syndrome in pigs and chickens.

Keywords: validation, Bacillus-based fermented products, antibiotics alternative, domestic animals

 

This Article

Received: 21 Sep 2021

Accepted: 20 Oct 2021

Published online: 29 Dec 2021

Accesses: 23

How to cite

Cheng, Y., Horng, Y., Chen, W., Hua, K., Dybus, A., Hsiao, F.S., Yu, Y., (2021). Development and validation the efficacy of Bacillus-based fermented products as an antibiotics alternative in domestic animals. Acta Sci. Pol. Zootechnica, 20(3), 23–34. DOI: 10.21005/asp.2021.20.3.03.