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Review Article

Characteristic of morphological changes of the spine in selected mammal species

Paulina Jundziłł-Bogusiewicz ¹ , Joanna Gruszczyńska ¹, Ivan Shuvar ², Krzysztof Papis ³

¹Department of Animal Genetics and Conservation, Warsaw University of Life Sciences – SGGW, Ciszewskiego 8, 02-786 Warsaw, Poland

²Lviv National Agrarian University, Volodymyra Velykoho 1, Dubliany, Lviv Oblast, Ukraine

³Center of Translational Medicine, Warsaw University of Life Sciences – SGGW, Nowoursynowska 100, 02-797 Warsaw, Poland

1. Acta Sci. Pol. Zootechnica, 20(3), 2021, 77‒84
2. DOI: 10.21005/asp.2021.20.3.11

Abstract. Morphological changes of the vertebrae, whether congenital or acquired, are more and more frequent causes of movement difficulties of both humans and other species of mammals. The most frequently diagnosed pathologies of the spine include: degenerative changes, congenital defects, inflammatory diseases, and proliferative changes. This article presents the characteristics of selected morphological changes in the spine, the reasons for their occurrence, and the diagnosis. Some of abnormalities have a genetic basis, sometimes already known, such as in the case of vertebral deformity syndrome in domestic cattle, which is caused by a mutation in the SLC35A3 gene. At other times, the genetic factor is only speculated as in the case of human scoliosis - some studies indicate its autosomal dominant nature of inheritance.

Keywords: morphological changes, spine, SLC35A3 gene, human, dog